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Serious underlying illness and the presence of other concurrent diseases place the patient at increased risk of CDI, especially if the patient is receiving additional antibiotics for concurrent infections 120 citrades no deposit bonus 2017 op iuni binare $12000 has a longer hospital stay. As many risk factors for CDI are correlated, multivariate analysis provides independent risk estimates for variables that occur at the same time.
Most multivariate models find advanced age, antibiotic use, co-morbidities, and longer hospital stays are independently predictive of CDI (211,214,232). Although several studies have not shown an association with proton pump inhibitors (PPIs) and CDI, many other studies have found an association (235,236). In a prospective study of 209 patients with recurrent CDI, logistic regression revealed only two significant independent risk factors for CDI recurrence: increased age and a lower quality of health at enrollment (238).